Zombie Autopsy Brain Lab – Interactive Neuroscience Lesson for Middle & High School
Digital Anatomy Investigation Using Symptoms to Identify Brain Structure Functions
Turn your classroom into a forensic neuroscience lab with this unforgettable interactive zombie autopsy lesson!
Students examine zombie symptoms, analyze brain structure functions, drag and reveal hidden anatomical diagrams, compare healthy vs. damaged regions, and ultimately write a case study explaining the cause of the zombie's behavior.
This lesson transforms abstract neuroscience into an accessible, engaging, and highly visual experience that students love. Perfect for middle and high school biology, neurology units, early-year engagement, or a Halloween-themed lesson that still meets rigorous learning standards.
⭐ What’s Included
Interactive Google Slides Lesson featuring drag-and-drop manipulation, GIFs, anatomical diagrams, and embedded clues
Guided CER (Claim–Evidence–Reasoning) Autopsy Tasks for each major brain region
Healthy vs. Zombie Brain Comparison Activities
EEG & Amygdala/Hypothalamus Scan Analysis for deeper critical thinking
Three-Paragraph Summative Case Study
Teacher Key
Printable Exit Ticket
Editable structure — differentiate by removing or adding brain regions
⭐ Skills Students Will Build
✓ Identifying major brain structures and their functions ✓ Using symptoms to diagnose neurological damage ✓ Supporting claims with anatomical evidence ✓ Analyzing real-world-style diagnostic data (EEG scans, imaging patterns) ✓ Writing an evidence-based neuroscience case report
⭐ Why Teachers Love It
No prep — complete digital lesson
Perfect blend of rigor + engagement
Memorable phenomenon-based learning
Students take ownership of investigation and reasoning
Works for 1:1 Chromebook, in-person, hybrid, or independent work
Bring neuroscience to life with a high-interest autopsy simulation students will talk about all year!
Grade & Course Recommendations
Middle School: Grades 7–8 (nervous system intro, structure & function)
High School: Biology, Anatomy & Physiology, Neuroscience elective
Also fits: Psychology, Forensics (for conceptual intro to brain systems)
Cross-Curricular Connections / Extensions
ELA: Evidence-based writing, case study construction, CER structure
Health / Psychology: Emotional regulation, memory formation, brain–behavior relationships
Forensic Science: Autopsy procedure, interpreting evidence
Art / Media: Analyze portrayals of zombies in media vs. real brain dysfunction
Technology: EEG interpretation, analyzing imaging data
Daily slide + literacy - based exit ticket included with purchase
Join the Lesson Laboratory and Teach for Tomorrow!
NGSS Alignment
Middle School NGSS
MS-LS1-3:
Use argument supported by evidence to explain how the body is a system of interacting subsystems.
→ Students link zombie symptoms to brain structures.
MS-LS1-8:
Gather and synthesize information that sensory receptors respond to stimuli…
→ Slides 5–6 ask students to analyze sensory changes.
High School NGSS
HS-LS1-1:
Structure determines function.
→ Entire autopsy hinges on linking damaged structures to impaired function.
HS-LS1-2:
Model the hierarchical organization of interacting systems.
→ Students consider sensory, motor, autonomic, emotional, and memory systems.
HS-LS1-3:
Feedback mechanisms maintain homeostasis.
→ Brainstem and hypothalamus analysis relates directly to regulation.
Science & Engineering Practices (SEPs)
Analyzing & Interpreting Data: EEG scans, symptom lists, comparative brain diagrams
Engaging in Argument from Evidence: CER tasks for each brain region
Constructing Explanations: Final multi-paragraph case study
Developing & Using Models: Students map symptoms onto anatomical models/slides
Crosscutting Concepts (CCCs)
Structure & Function: Central theme; students must justify functional loss
Systems & System Models: Brain subsystems (sensory, motor, autonomic, emotional)
Cause & Effect: Linking neural damage → zombie symptoms
Stability & Change: Normal vs. disrupted neurological homeostasis
Common Core Standards
Middle & High School ELA
CCSS.ELA-LITERACY.RST.6-8.1 / RST.9-10.1
Citing evidence from scientific texts/images (symptoms, scans)
CCSS.ELA-LITERACY.RST.6-8.7 / RST.9-10.7
Integrating visual information (EEG, imaging, diagrams)
CCSS.ELA-LITERACY.WHST.6-8.2 / WHST.9-10.2
Informational/explanatory scientific writing
CCSS.ELA-LITERACY.WHST.6-8.9 / WHST.9-10.9
Evidence-based reasoning using scientific sources
Digital Anatomy Investigation Using Symptoms to Identify Brain Structure Functions
Turn your classroom into a forensic neuroscience lab with this unforgettable interactive zombie autopsy lesson!
Students examine zombie symptoms, analyze brain structure functions, drag and reveal hidden anatomical diagrams, compare healthy vs. damaged regions, and ultimately write a case study explaining the cause of the zombie's behavior.
This lesson transforms abstract neuroscience into an accessible, engaging, and highly visual experience that students love. Perfect for middle and high school biology, neurology units, early-year engagement, or a Halloween-themed lesson that still meets rigorous learning standards.
⭐ What’s Included
Interactive Google Slides Lesson featuring drag-and-drop manipulation, GIFs, anatomical diagrams, and embedded clues
Guided CER (Claim–Evidence–Reasoning) Autopsy Tasks for each major brain region
Healthy vs. Zombie Brain Comparison Activities
EEG & Amygdala/Hypothalamus Scan Analysis for deeper critical thinking
Three-Paragraph Summative Case Study
Teacher Key
Printable Exit Ticket
Editable structure — differentiate by removing or adding brain regions
⭐ Skills Students Will Build
✓ Identifying major brain structures and their functions ✓ Using symptoms to diagnose neurological damage ✓ Supporting claims with anatomical evidence ✓ Analyzing real-world-style diagnostic data (EEG scans, imaging patterns) ✓ Writing an evidence-based neuroscience case report
⭐ Why Teachers Love It
No prep — complete digital lesson
Perfect blend of rigor + engagement
Memorable phenomenon-based learning
Students take ownership of investigation and reasoning
Works for 1:1 Chromebook, in-person, hybrid, or independent work
Bring neuroscience to life with a high-interest autopsy simulation students will talk about all year!
Grade & Course Recommendations
Middle School: Grades 7–8 (nervous system intro, structure & function)
High School: Biology, Anatomy & Physiology, Neuroscience elective
Also fits: Psychology, Forensics (for conceptual intro to brain systems)
Cross-Curricular Connections / Extensions
ELA: Evidence-based writing, case study construction, CER structure
Health / Psychology: Emotional regulation, memory formation, brain–behavior relationships
Forensic Science: Autopsy procedure, interpreting evidence
Art / Media: Analyze portrayals of zombies in media vs. real brain dysfunction
Technology: EEG interpretation, analyzing imaging data
Daily slide + literacy - based exit ticket included with purchase
Join the Lesson Laboratory and Teach for Tomorrow!
NGSS Alignment
Middle School NGSS
MS-LS1-3:
Use argument supported by evidence to explain how the body is a system of interacting subsystems.
→ Students link zombie symptoms to brain structures.
MS-LS1-8:
Gather and synthesize information that sensory receptors respond to stimuli…
→ Slides 5–6 ask students to analyze sensory changes.
High School NGSS
HS-LS1-1:
Structure determines function.
→ Entire autopsy hinges on linking damaged structures to impaired function.
HS-LS1-2:
Model the hierarchical organization of interacting systems.
→ Students consider sensory, motor, autonomic, emotional, and memory systems.
HS-LS1-3:
Feedback mechanisms maintain homeostasis.
→ Brainstem and hypothalamus analysis relates directly to regulation.
Science & Engineering Practices (SEPs)
Analyzing & Interpreting Data: EEG scans, symptom lists, comparative brain diagrams
Engaging in Argument from Evidence: CER tasks for each brain region
Constructing Explanations: Final multi-paragraph case study
Developing & Using Models: Students map symptoms onto anatomical models/slides
Crosscutting Concepts (CCCs)
Structure & Function: Central theme; students must justify functional loss
Systems & System Models: Brain subsystems (sensory, motor, autonomic, emotional)
Cause & Effect: Linking neural damage → zombie symptoms
Stability & Change: Normal vs. disrupted neurological homeostasis
Common Core Standards
Middle & High School ELA
CCSS.ELA-LITERACY.RST.6-8.1 / RST.9-10.1
Citing evidence from scientific texts/images (symptoms, scans)
CCSS.ELA-LITERACY.RST.6-8.7 / RST.9-10.7
Integrating visual information (EEG, imaging, diagrams)
CCSS.ELA-LITERACY.WHST.6-8.2 / WHST.9-10.2
Informational/explanatory scientific writing
CCSS.ELA-LITERACY.WHST.6-8.9 / WHST.9-10.9
Evidence-based reasoning using scientific sources